Catécholamine
カテコールアミン
카테콜아민
Catecholamine
Catecolamina
儿茶酚胺
Katekolamin
كاتيكولامين
Katekolamina
Катехоламины
Катехоламіни
Katecholaminy
Katecholamin
Κατεχολαμίνη
Katecholamine
Catacólaimín
Adrenalin - Adrenaline.svg
Dopamin - Dopamine.svg
Noradrenalin - Noradrenaline.svg
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Catecholamines
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Aminen taldeko substantzia, neurotransmisore-funtzioa betetzen duena. Adrenalina, noradrenalina eta dopamina dira katekolamina nagusiak
תרכובת אורגנית
compuesto orgánico
composé organique
4-(2-aminoethyl)pyrocatechol and derivatives formed by substitution
화합물의 부류
organisk sambinding med ein katekol og eit sidekjedeamin
każdy związek chemiczny zawierający w swojej strukturze szkielet 4-(2-aminoetylo)benzeno-1,2-diolu
organische Verbindungen, Arzneistoffe, Dopamin-Derivate
(L)-Phenylalanine is converted into (L)-tyrosine by an aromatic amino acid hydroxylase (AAAH) enzyme , with molecular oxygen and tetrahydrobiopterin as cofactors. (L)-Tyrosine is converted into (L)-DOPA by another AAAH enzyme with tetrahydrobiopterin, O2, and ferrous iron as cofactors. (L)-DOPA is converted into dopamine by the enzyme aromatic (L)-amino acid decarboxylase (AADC), with pyridoxal phosphate as the cofactor. Dopamine itself is also used as precursor in the synthesis of the neurotransmitters norepinephrine and epinephrine. Dopamine is converted into norepinephrine by the enzyme dopamine β-hydroxylase (DBH), with O2 and (L)-ascorbic acid as cofactors. Norepinephrine is converted into epinephrine by the enzyme phenylethanolamine N-methyltransferase with S-adenosyl-(L)-methionine as the cofactor.
In humans, catecholamines are derived from the amino acid (L)-phenylalanine.