| dbp:shortsummary
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- 1.57788E9 (dbd:second)
- Burned out after the last several months, Grissom announced his coming retirement, but is willing to stay on for one more case: when a new murder leads to a connection with an infamous serial killer, "The Dick and Jane Killer" Nate Haskell , Grissom secretly joins the class of well-known criminal pathologist Dr. Raymond Langston , to gain access to the killer and get a crack in the case. (en)
- The team must find out who tipped a biker gang off after an undercover cop in their midst is murdered. While the investigation of crime lab uncover the story behind the crime scene, they discover the tragic truth that was covered within the evidence from the crime scene. (en)
- The CSIs must help the victim's partner find the killer of an undercover FBI agent, who was found brutally murdered at a gas station restroom. A huge muscular man, later revealed to be a mixed martial arts fighter, was the prime suspect who later, under influence of drugs, killed himself during a MMA tournament. The CSIs would proceed to find his accomplice, in which they would uncover an underground sex ring. (en)
- On Nick's birthday, a murder of a resident at a seedy motel led to him reminiscing about its inhabitants and the numerous murders there over the course of a year and a possible connection with all of them - and a personal interest in the latest victim. (en)
- Nick and Catherine investigate why a woman who was about to be married would have taken a swan dive off of her balcony onto a city bus; they would later discover that it was murder by hypnosis. They would also find out that hypnosis played in a role of a bank robbery, with both crimes being connected. Also: Grissom investigates the brutal murder of a woman found in an alley. The investigation gets tougher with the discovery that her two-year-old was with her when she was murdered, later abandoned at a day care at a local casino. Greg calls Sara in to work with Detective Sam Vega on a case related to one of her first cases: when the husband of a woman, who was raped and left comatose in the Season 1 episode "Too Tough to Die", pulls out her breathing tube; as she was personally vested in that case, and still reeling over the events over Warrick and herself, Sara would return to San Francisco, still not ready to return to her career. (en)
- Langston, Nick and Riley investigate a murder at a fast food restaurant that turns out to be difficult because most of their evidence is coated in cooking oil. Meanwhile, Catherine and Greg investigate the strange death of a woman killed by ingesting two tubes of toothpaste. (en)
- In the 200th episode, a young woman, who became sick after consuming an alcoholic beverage during a lucha libre match, was murdered by a man wearing a wrestler's "máscara" . Ray would determine that she was a former student of his, with plans on becoming a CSI; further investigation would link that murder to several other women, who, just like this victim, had their neck broken. The only tangible evidence to go by was a piece of leather torn from the mask. (en)
- The team investigate a suspected body dump just outside The Strip and discover that a stash of chips from a defunct casino worth upwards to thousands of dollars each on the collectible market may be the key to solving the murder. In doing their research, they discovered that many of the chips were supposed to have been destroyed, and a discovery of a stash of these chips could affect their value. (en)
- A mutilated body with much of its face missing was found in the desert and the man's girlfriend is missing. After discovering needle marks on the victim's body, Grissom turns to Lady Heather for help when he realizes that the needle marks are a form of S&M. She points the team towards a bar designed for poetry and performing arts, but it has a secret back room perfect for S&M fantasies, including apparatus that could have killed the victim. Meanwhile, Sara, sailing "south of the Equator", e-mailed a video to Grissom, which she questions his commitment; with developments involving Warrick and Sara beginning to affect him emotionally, Grissom seeks Lady Heather's advice on his personal matters. (en)
- Greg, Riley, and Brass investigate the death of a woman and the beating of her daughter who falls into a coma. They discover the woman's husband is a suspect in the murder of a private investigator, Trevor Murphy and Trevor's kids may be bent on getting revenge for their dad's murder, at any cost. Also: Catherine and Nick investigate when two teenagers crash their car into a tree and die and uncover a deadly game of mailbox baseball, in which a neighbor rigged the "score" in his favor. In the meantime, Grissom attends Natalie Davis' court hearing, to determine whether she's mentally fit to serve her sentence in prison. (en)
- The CSIs investigate a drug-related shootout that leaves three people dead and two teenagers missing, in a usually calm Las Vegas neighborhood. Later, when Langston and Riley investigate a drug lab, they stumble upon the two missing teens - one of them critically injured in dire need of medical care, the other taking Langston and Riley hostage by gunpoint. (en)
- While at a sci-fi convention, Hodges and Wendy stumble across the body of a dead producer, after he faced criticism over his revamping of a revered sci-fi franchise, "Astro Quest". While the team works to solve the case, Hodges daydreams that he and Wendy are stars on an "Astro Quest" episode; they both must deal with the fact that they may be falling for each other. (en)
- It is Halloween and Nick and Riley witness a man dressed as a cop rob a convenience store; a foot chase would later end with the suspect landing in a dumpster filled with glass shards, killing him instantly, but Nick and Riley discovered that he was not alone when they find a dead woman in that same dumpster. That woman was discovered to be the daughter of a major drug lord, which leads them to a seedy club where Catherine finds her daughter Lindsey on the dance floor, who entered the club with a fake ID. Wendy and Dr. Robbins clash when the victim is revealed to have three blood types in her body and two of them are male. (en)
- The CSI team works to close Grissom's last open case, for which Dr. Langston joins the team as consultant for the case; they discovered that the clues to the murders, Haskell's accomplice, and their missing victims, can be found in the professor's classroom. However, after finding the latest male victim in the previous episode, they have limited time to find his missing girlfriend before the killer dispatches her. Before his departure, Grissom offers the job opening for the professor, after conferring with Ecklie, who became the new Undersheriff. (en)
- When a seasoned skydiver is paralyzed after free falling to earth when his parachute does not deploy, he turns out to be linked to the strange death-by-airborne-toxins of two wealthy men with ties to Iran. Also: Langston investigates the death of a leader of a religious storefront temple, whose only footprints in the desert were the victim's. (en)
- After being cleared of the murder of mobster Lou Gedda, CSI Warrick Brown is shot and killed outside a Las Vegas diner. The entire team grieves for their fallen friend, while unknown to them, the killer is one of their own, who is on the lam with Gedda's murderer - also one of their own. Also, Sara returns to Las Vegas when she hears the news, lending the hand to Grissom's crew as they insisted on helping to solve the case for Warrick. (en)
- Dr. Langston's first day as a CSI is anything but easy when a seemingly simple burglary case ends up overlapping with an in-depth homicide and arson case. (en)
- Robbins and Catherine follow up with a woman, who was a next-of-kin to a man who recently died; after Catherine entered the house, the woman viciously attacked her and bit her in the hand before collapsing and dying. Soon, Robbins inspected deaths of three men, all of them having died of the same disease as the woman, which turned out to be rabies. The trail would lead them to a tattoo parlor, where one of its employees was a doctor who won a lawsuit regarding rabies years earlier. Meanwhile, Greg and Riley investigate when a friendly rivalry over who will win an upcoming bikini contest takes a deadly turn when one of the contestants is sexually assaulted before dying in hospital; in actuality, it was a food fight gone violent. (en)
- The CSIs are called to three different crime scenes in one night: Ray and Wendy investigate the murder of an art dealer, Catherine and Greg investigate the murder of a woman in a motel, whilst Nick and Riley investigate the death of a man found stuffed in a car. The cases initially seem unrelated, but forensic evidence in each of them reveals a common link. (en)
- While Langston testifies in the trial of a respected Congressman, the prosecution's key witness commits suicide outside the court with the suspected murder weapon sending the CSIs back to the lab. (en)
- Catherine looks into one of her first cases as a CSI when a man claims that the verdict was influenced by faulty forensics, citing that advancements over the years might give him a second chance. (en)
- The CSI team investigates a shooting at a Koreatown neighborhood party, in which the mother and uncle of a small boy, Park Bang, are murdered. Grissom stakes a personal investment in the case when it is discovered that Park Bang witnessed the shooting and he goes missing. Grissom suspects the killer tracked Park down and is trying to keep him from talking. The case becomes more complicated when it's revealed Park has HIV and his mother put him on an unauthorized medical trial. (en)
- The team investigates the murder of a woman found in the park posed to recreate life and a string of murders follows with the same pattern. An artist becomes one of the suspects when they find out he has his models pose as dead bodies for his paintings. He would be cleared after discovering another artist who openly confessed to using murder as an art form to imitate life; the case would become much more urgent after discovering that one of his future "installations" would involve a child. Also, being two CSIs short, Ecklie hires a new CSI, Riley Adams , and a counselor comes in to help them deal with Warrick's death; Riley would take offense with the counselor when she began quizzing her about her grief, despite having just walked in to begin her first day and not even knowing anyone involved. Grissom, though still not overtly open with his grief, is showing signs of burn out when he had made mistakes in lab procedure. (en)
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