About: First pass effect

Property	Value
dbo:description	Umwandlung eines Arzneistoffes während dessen erster Passage durch die Leber (de) 약물이 체순환에 도달하기 전 대사되어 생체이용률이 감소하는 현상 (ko) ilaç metabolizması olgusu (tr) phenomenon of drug metabolism (en) phénomène de métabolisation d'un médicament (fr) pojav pri presnovi zdravil, ko se del učinkovine metabolizira, še preden vstopi v sistemski krvni obtok (sl) 药代动力学术语 (zh)
dbo:thumbnail	wiki-commons:Special:FilePath/2138_Hepatic_Portal_Vein_System.jpg?width=300
dbo:wikiPageExternalLink	https://web.archive.org/web/20100611064829/http:/sis.nlm.nih.gov/enviro/toxtutor/Tox2/a32.htm http://sis.nlm.nih.gov/enviro/toxtutor/Tox2/a32.htm
dbo:wikiPageWikiLink	dbr:Lumen_(anatomy) dbr:Transdermal_patch dbr:Chlorpromazine dbr:Imipramine dbr:Bioavailability dbr:Lidocaine dbr:Enteral_administration dbr:Drug_metabolism dbc:Medicinal_chemistry dbr:Medication dbr:Systemic_circulation dbr:Pharmacology dbr:Insulin dbr:Hepatic_portal_system dbr:Morphine dbr:Buprenorphine dbr:Cimetidine dbr:Clomethiazole dbr:Partition_coefficient dbr:Circulatory_system dbr:Ethanol dbr:Metabolism dbr:Diazepam dbr:Parenteral dbr:Route_of_administration dbr:Concentration dbr:Insufflation_(medicine) dbr:Drug dbr:Enzyme dbr:Gastrointestinal_tract dbr:Liver dbr:SARS-CoV-2 dbr:Benzylpenicillin dbr:ADME dbr:Midazolam dbr:Propranolol dbr:Tetrahydrocannabinol dbr:Biopharmaceutics_Classification_System dbr:Suppository dbr:Metered-dose_inhaler dbr:Pethidine dbc:Pharmacokinetics dbr:Pharmacokinetics dbr:Drug_design dbr:National_Library_of_Medicine dbr:Druglikeness dbr:Active_pharmaceutical_ingredient dbr:Intravenous dbr:Remdesivir dbr:Sublingual dbr:Digestive_system dbr:Hepatic_portal_vein dbr:Intramuscular dbr:File:2138_Hepatic_Portal_Vein_System.jpg
dbp:date	2010-06-11 (xsd:date)
dbp:pages	4 (xsd:integer)
dbp:url	https://web.archive.org/web/20100611064829/http:/sis.nlm.nih.gov/enviro/toxtutor/Tox2/a32.htm
dbp:wikiPageUsesTemplate	dbt:Ambiguous dbt:More_citations_needed dbt:Distinguish dbt:Rp dbt:Webarchive dbt:Short_description
dct:subject	dbc:Medicinal_chemistry dbc:Pharmacokinetics
gold:hypernym	dbr:Phenomenon
rdfs:label	First pass effect (en) تأثير المرور الأولي (ar) Efekt prvního průchodu (cs) First-Pass-Effekt (de) Effet de premier passage (fr) Effetto di primo passaggio (it) 初回通過効果 (ja) 초회 통과 효과 (ko) Efekt pierwszego przejścia (pl) Metabolismo de primeira passagem (pt) First-pass-effect (nl) Förstapassagemetabolism (sv) Эффект первого прохождения (ru) 首过效应 (zh)
owl:differentFrom	dbr:First-dose_phenomenon
owl:sameAs	freebase:First pass effect yago-res:First pass effect wikidata:First pass effect dbpedia-it:First pass effect dbpedia-nl:First pass effect dbpedia-de:First pass effect dbpedia-fr:First pass effect dbpedia-tr:First pass effect dbpedia-zh:First pass effect dbpedia-ja:First pass effect dbpedia-pt:First pass effect dbpedia-ro:First pass effect dbpedia-fa:First pass effect dbpedia-ru:First pass effect dbpedia-sv:First pass effect dbpedia-pl:First pass effect dbpedia-ko:First pass effect dbpedia-et:First pass effect dbpedia-ar:First pass effect dbpedia-cs:First pass effect dbpedia-fi:First pass effect dbpedia-ku:First pass effect dbpedia-la:First pass effect dbpedia-sh:First pass effect dbpedia-sl:First pass effect dbpedia-sr:First pass effect dbpedia-global:First pass effect dbr:First pass effect
prov:wasDerivedFrom	wikipedia-en:First_pass_effect?oldid=1296049333&ns=0
foaf:depiction	wiki-commons:Special:FilePath/2138_Hepatic_Portal_Vein_System.jpg
foaf:isPrimaryTopicOf	wikipedia-en:First_pass_effect
is dbo:wikiPageRedirects of	dbr:First-pass_effect dbr:First-pass_metabolism dbr:First_pass dbr:First_pass_metabolism dbr:Presystemic_metabolism
is dbo:wikiPageWikiLink of	dbr:Congenital_portosystemic_shunt dbr:Tilidine dbr:Amitriptyline dbr:Heroin dbr:Drug_interaction dbr:Drug_metabolism dbr:Injection_(medicine) dbr:Opiate dbr:Idebenone dbr:Rectal_venous_plexus dbr:Organ-on-a-chip dbr:Collagenous_colitis dbr:Olanzapine dbr:Oxybutynin dbr:Drug_injection dbr:Hepatic_portal_system dbr:Bupropion dbr:Dihydrotestosterone dbr:Paroxetine dbr:Pentobarbital dbr:Testosterone dbr:Tetrabenazine dbr:Testosterone_(medication) dbr:First-dose_phenomenon dbr:Route_of_administration dbr:Antiandrogen dbr:Pentoxyverine dbr:H3_receptor_antagonist dbr:Lamivudine/zidovudine dbr:Drug_tolerance dbr:Benperidol dbr:Biperiden dbr:Budesonide dbr:Domperidone dbr:Fluvastatin dbr:Lacosamide dbr:Loperamide dbr:Misoprostol dbr:Moclobemide dbr:Nabilone dbr:Praziquantel dbr:Sibutramine dbr:Tapentadol dbr:Erdosteine dbr:Mesenchymal_stem_cell dbr:Dopamine_agonist dbr:Dopamine_antagonist dbr:Flavin-containing_monooxygenase dbr:Discovery_and_development_of_antiandrogens dbr:Discovery_and_development_of_cyclooxygenase_2_inhibitors dbr:Discovery_and_development_of_triptans dbr:Biopharmaceutics_Classification_System dbr:Management_of_Crohn's_disease dbr:Sublingual_administration dbr:O-Acetylpsilocin dbr:Mitratapide dbr:Pharmacokinetics_of_testosterone dbr:Pulmonary_drug_delivery dbr:Buccal_tablet dbr:Upadacitinib dbr:Selegiline dbr:First-pass_effect dbr:First-pass_metabolism dbr:First_pass dbr:First_pass_metabolism dbr:Presystemic_metabolism
is foaf:primaryTopic of	wikipedia-en:First_pass_effect