About: Genome instability

An Entity of Type: Thing, from Named Graph: http://dbpedia.org, within Data Space: dbpedia-live.demo.openlinksw.com

High frequency of mutations within the genome of a cellular lineage

Property	Value
dbo:description	high frequency of mutations within the genome of a cellular lineage (en)
dbo:thumbnail	wiki-commons:Special:FilePath/Inestabilidad_genómica-Aneuploidía.jpg?width=300
dbo:wikiPageWikiLink	dbr:Nucleic_acid_sequence dbr:Neoplasm dbr:Chromosomal_inversion dbr:Non-homologous_end_joining dbr:Alzheimer's_disease dbc:Cancer dbr:Follicular_lymphoma dbr:Trichothiodystrophy dbr:Diploid dbr:Xeroderma_pigmentosum dbr:Mantle_cell_lymphoma dbr:Deletion_(genetics) dbr:Biological_target dbr:Spinocerebellar_ataxia dbr:MicroRNA dbr:DNA_repair dbr:DNA dbr:Aneuploidy dbr:Nijmegen_breakage_syndrome dbc:Chromosomes dbr:Chromosome dbr:Exome dbr:Huntington's_disease dbr:Karyotype dbr:Cancer dbr:Myotonic_dystrophy dbr:Parkinson's_disease dbr:DNA_damage_(naturally_occurring) dbr:Mutation dbr:Genotoxicity dbr:Chromosomal_rearrangement dbr:Bloom_syndrome_protein dbr:Chromosomal_translocation dbr:Caretaker_gene dbr:ERCC1 dbr:FANCB dbr:FANCF dbr:Epigenetics dbr:Exogeny dbr:Tumor_microenvironment dbr:DNA_mismatch_repair dbr:Cancer_epigenetics dbr:Triple-A_syndrome dbr:Cyclin_D1 dbr:Amyotrophic_lateral_sclerosis dbr:Gatekeeper_gene dbr:Homologous_recombination dbr:NEIL1 dbr:Down's_syndrome dbr:BRCA1 dbr:MSH4 dbr:Activation-induced_cytidine_deaminase dbr:WRN_(gene) dbr:MLH1 dbr:MSH2 dbr:Tumour_heterogeneity dbr:Ataxia_telangiectasia_mutated dbr:Neurodegeneration dbr:O-6-methylguanine-DNA_methyltransferase dbr:Noncoding_DNA dbr:C-myc dbr:Friedreich’s_ataxia dbr:Double-strand_break dbr:Cockayne's_syndrome dbr:Ataxia-telangiectasia dbr:List_of_number_of_chromosomes_of_various_organisms dbr:Replication_stress dbr:Tumorogenesis dbr:Translesion_synthesis
dbp:wikiPageUsesTemplate	dbt:Main dbt:Reflist dbt:See_also dbt:Portal_bar dbt:Citation_needed dbt:Cn dbt:Short_description
dct:subject	dbc:Mutation dbc:Cancer dbc:Chromosomes
rdf:type	owl:Thing
rdfs:label	Genome instability (en) عدم استقرار الجينوم (ar) Inestabilidad genómica (es) ゲノム不安定性 (ja) Геномная нестабильность (ru)
rdfs:seeAlso	dbr:Hallmarks_of_aging
owl:sameAs	yago-res:Genome instability freebase:Genome instability wikidata:Genome instability dbpedia-ja:Genome instability dbpedia-he:Genome instability dbpedia-es:Genome instability dbpedia-ru:Genome instability dbpedia-ar:Genome instability dbpedia-gl:Genome instability dbpedia-global:Genome instability dbr:Genome instability
skos:closeMatch	http://www.springernature.com/scigraph/things/subjects/genomic-instability
prov:wasDerivedFrom	wikipedia-en:Genome_instability?oldid=1296323930&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Inestabilidad_genómica-Aneuploidía.jpg
foaf:isPrimaryTopicOf	wikipedia-en:Genome_instability
is dbo:academicDiscipline of	dbr:Laurence_Pearl
is dbo:knownFor of	dbr:Sergei_Mirkin dbr:Peter_M._Lansdorp
is dbo:wikiPageRedirects of	dbr:Genetic_instability dbr:Genomic_instability
is dbo:wikiPageWikiLink of	dbr:Plasma_cell_leukemia dbr:Sergei_Mirkin dbr:Ageing dbr:Heterochromatin dbr:Sunlight dbr:Neoplasm dbr:Whole_genome_sequencing dbr:Downwinders dbr:Follicular_lymphoma dbr:Virus_latency dbr:Chromosome_instability dbr:Establishment_of_sister_chromatid_cohesion dbr:NEDD8 dbr:Rockefeller_University dbr:Enteropathy-associated_T-cell_lymphoma dbr:DNA_repair dbr:Malignancy dbr:Systems_biology dbr:Centrosome dbr:PUVA_therapy dbr:Evan_E._Eichler dbr:Progeroid_syndromes dbr:Radiobiology_evidence_for_protons_and_HZE_nuclei dbr:ERIBA dbr:Hallmarks_of_aging dbr:Cancer dbr:Carcinogenesis dbr:Antineoplastic_resistance dbr:Long_interspersed_nuclear_element dbr:DNA_re-replication dbr:Q-FISH dbr:Spindle_checkpoint dbr:The_Hallmarks_of_Cancer dbr:Malignant_transformation dbr:Post-transcriptional_regulation dbr:P53 dbr:Caretaker_gene dbr:Ribose-seq dbr:LIG1 dbr:Tumor_microenvironment dbr:Cancer_epigenetics dbr:Somatic_evolution_in_cancer dbr:Telomeric_repeat–containing_RNA dbr:Laurence_Pearl dbr:Tumor_mutational_burden dbr:Pevonedistat dbr:Primary_testicular_diffuse_large_B-cell_lymphoma dbr:MCM8 dbr:Biological_effects_of_radiation_on_the_epigenome dbr:APPBP1 dbr:DNA-PKcs dbr:TPX2 dbr:HMGA2 dbr:PARP1 dbr:MiR-155 dbr:DRIP-seq dbr:Lumír_Krejčí dbr:Lifespan:_Why_We_Age_–_and_Why_We_Don't_Have_To dbr:Batsheva_Kerem dbr:Tumour_heterogeneity dbr:Rong_Li dbr:DNA_replication_stress dbr:Yimon_Aye dbr:Jan_Karlseder dbr:Genetic_instability dbr:Genomic_instability dbr:PMS2
is rdfs:seeAlso of	dbr:Hallmarks_of_aging
is foaf:primaryTopic of	wikipedia-en:Genome_instability